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fluvoxamine will improve the amount or effect of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Contraindicated (1)nirmatrelvir/ritonavir will enhance the stage or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Stiripentol is actually a CYP3A4 inhibitor and inducer. Monitor CYP3A4 substrates coadministered with stiripentol for amplified or lessened outcomes. CYP3A4 substrates may possibly need dosage adjustment.
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Check Intently (1)ergotamine will enhance the stage or impact of finerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pipemidic acid will boost the degree or impact of caffeine by impacting hepatic enzyme CYP1A2 metabolism. Insignificant/Significance Unfamiliar.
duvelisib will raise the stage or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration with duvelisib raises etizolam powder usa vendor AUC of a sensitive CYP3A4 substrate which may raise the chance of toxicities of such medications.
givosiran will improve the stage or effect of caffeine by affecting hepatic enzyme CYP1A2 metabolism.
etravirine will minimize the extent or effect of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
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Voxelotor increases systemic publicity of sensitive CYP3A4 substrates. Keep away from coadministration with sensitive CYP3A4 substrates using a narrow therapeutic index. Think about dose reduction on the delicate CYP3A4 substrate(s) if not able to stay clear of.
bremelanotide will decrease the extent or outcome of ergotamine by Other (see remark). Keep away from or Use Alternate Drug. Bremelanotide may possibly sluggish gastric emptying and potentially lessens the rate and extent of absorption of concomitantly administered oral remedies.
dasatinib will raise the stage or outcome of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.